Physician Assistant - Plymouth, MA - Clinical Research

Headlands Research

🏠 Remote
📍Plymouth, MA
Posted May 22, 2026

Job Overview

Position

Physician Assistant - Plymouth, MA - Clinical Research

Company

Headlands Research

Location

Plymouth, MA

Work Type

Remote

Job ID

li-4416757063

Job Description

At Headlands Research, we are dedicated to enhancing clinical trial delivery within our communities. As a leading network of advanced clinical trial sites, we leverage cutting-edge technology and exceptional support services to broaden outreach and participation. Founded in 2018, our rapidly growing company currently operates 20+ sites across the US and Canada, with plans for further expansion.

Championing Diversity in Clinical Trials

At Headlands Research, diversity is not just a goal — it is foundational to how we advance medicine. We are committed to improving representation in clinical research and ensuring patients from all backgrounds have access to innovative treatment opportunities. From the patients we serve to the teams we build, inclusivity is embedded into everything we do.

Make a Meaningful Impact in Dementia & Neurology Research

Headlands Research Eastern Massachusetts, in partnership with Seacoast Neurology Group, is seeking an experienced Nurse Practitioner or Physician Assistant to join our growing clinical research team as a Sub-Investigator in Plymouth, Massachusetts.

This role is ideal for an advanced provider who is passionate about caring for adult and geriatric patients - particularly those affected by Alzheimer’s disease, dementia, and other neurological conditions - and who wants to play a direct role in advancing future treatments through clinical research.

We are especially interested in connecting with providers who live within a commutable distance to Plymouth and who value building strong relationships with patients and caregivers in a collaborative, patient-centered environment.

Why Join Us?

Meaningful Work in Dementia Research

Help bring innovative therapies to patients living with Alzheimer’s disease and related dementias while supporting families navigating complex neurological conditions.

Collaborative Neurology-Focused Environment

Work alongside experienced neurologists, clinical research coordinators, raters, and patient recruitment specialists as part of both Headlands Research and Seacoast Neurology Group.

Supportive, High-Performing Culture

Our teams value professionalism, accountability, compassion, and collaboration. You will be supported by experienced research staff while having the opportunity to grow your clinical research experience and leadership skills.

Location:
Onsite in Plymouth, Massachusetts (no remote or hybrid opportunities)

Schedule:
Full-Time | Monday through Friday

Pay:
$120,000 - 140,000/yr (dependent upon years of experience, certifications, and education)

Responsibilities

  • Ensure the safety and welfare of clinical trial participants

  • Conduct medical history reviews and physical examinations

  • Evaluate potential study participants according to protocol inclusion/exclusion criteria

  • Review EKGs, laboratory results, and other clinical assessments

  • Provide medical oversight and care throughout study participation

  • Develop strong rapport with dementia patients and caregivers through compassionate communication

  • Collaborate closely with neurologists, research coordinators, and sponsor representatives

  • Maintain in-depth knowledge of assigned research protocols

  • Attend Investigator Meetings on behalf of the Principal Investigator as needed

  • Support high-quality data collection and protocol compliance

  • Demonstrate professionalism, accountability, and strong patient-centered communication

Requirements

  • Minimum of 2 years of experience as a licensed Nurse Practitioner or Physician Assistant preferred; willing to consider new graduates

  • Current and unencumbered NP or PA license in the state of Massachusetts required

  • Experience working with adult and geriatric patient populations required

  • Prior experience caring for patients with dementia, Alzheimer’s disease, neurology, geriatrics, psychiatry, primary care, or related specialties strongly preferred

  • Clinical research experience preferred, but not required

  • Strong interpersonal skills with the ability to communicate effectively with cognitively impaired patients and caregivers

  • Highly organized with strong attention to detail

  • Professional, dependable, and collaborative demeanor

  • Passion for direct patient interaction and advancing medical research

  • Ability to thrive in a fast-paced, team-oriented clinical environment

About Headlands Research
Headlands Research is a leading integrated clinical trial site network with a mission to improve lives by advancing innovative medical therapies. Our sites partner with sponsors and CROs to conduct high-quality clinical trials across a variety of therapeutic areas while delivering exceptional patient care and operational excellence.

At our Eastern Massachusetts site, we are proud to partner closely with Seacoast Neurology Group to advance neurological and dementia-focused research within the local community.

*Headlands Research will never ask a candidate for personal identifiable information (date of birth, social security number, driver’s license information, etc) via email or messenger tools, or for a financial deposit of any kind.*
*Headlands Research is an Equal Opportunity Employer. We do not discriminate on the basis of race, color, religion, age, sex, national origin, disability status, genetic information, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.*
Need Assistance?

*Headlands Research is committed to providing access and reasonable accommodation in its employment for individuals with disabilities. To request disability accommodation in the application process, contact [email protected] for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.*

Interview Prep

AI-powered insights to help you prepare

Key Skills

Required:
Preferred:

Practice Questions

💡Technical Questions (3)
  • 1.How do you approach evaluating a potential clinical trial participant against strict protocol inclusion/exclusion criteria, particularly when dealing with an elderly patient presenting with mild cognitive impairment?
  • 2.What key clinical indicators do you monitor when reviewing EKGs and laboratory results for geriatric patients participating in neurology clinical trials?
  • 3.Can you describe your process for maintaining in-depth knowledge of a complex research protocol and ensuring high-quality data collection during patient visits?
🎯Behavioral Questions (3)
  • 1.Tell me about a time you had to deliver difficult news or explain a complex medical situation to a dementia patient and their caregiver. How did you ensure they felt supported and understood?
  • 2.Describe a situation where you had to collaborate with a multidisciplinary team—including physicians, coordinators, or specialists—to ensure a patient's safety and protocol compliance.
  • 3.Give an example of a time you championed diversity or inclusivity in your clinical practice, ensuring patients from all backgrounds had access to care or felt represented.
🧩Situational Questions (2)
  • 1.You are evaluating a patient for an Alzheimer's disease trial. The patient meets the inclusion criteria, but their caregiver expresses significant distress and hesitation about the potential side effects of the study drug. How do you handle this?
  • 2.During a routine study visit, a geriatric patient's lab results show an abnormality that falls just outside the protocol's safety parameters, but the Principal Investigator is unavailable for the next two hours. What is your immediate course of action?

Resume Keywords

Make sure these keywords appear on your resume

Physician AssistantSub-InvestigatorClinical ResearchDementiaAlzheimer's DiseaseGeriatricsNeurologyProtocol ComplianceInclusion/Exclusion CriteriaEKG InterpretationPatient-Centered CareCaregiver Communication

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